Disease Resistance Overview

Disease resistance refers to the ability of a plant or animal to prevent or limit infection by a pathogen such as a virus, bacteria, or fungus. There are several types of disease resistance:

  • Vertical Resistance - Resistance that protects against specific pathogen strains or races. This resistance is controlled by R genes and is usually race-specific.
  • Horizontal Resistance - Resistance that provides partial protection against all races of a pathogen. This form of resistance is more durable over time.
  • Induced Resistance - Resistance triggered by external factors. For example, some chemicals can switch on plant defense mechanisms against pathogens.

Plants have physical and chemical barriers to block pathogen invasion, as well as R genes that recognize specific pathogens and trigger defense responses. Common defenses include:

  • Cell Wall Thickening to block entry
  • Antimicrobial Compound Production to kill pathogens
  • Hypersensitive Response that isolates infection sites

Breeding for disease resistance aims to introduce R genes from wild relatives into cultivated varieties. Other strategies include gene editing techniques like CRISPR to disable susceptibility genes.

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